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Summary of drugs targeting cell cycle-related proteins and undergoing clinical research. Abbreviations: OS, osteosarcoma; LMS, leiomyosarcoma; SS, synovial sarcoma; OC, ovarian cancer; NSCLC, non-small cell lung cancer; PANC, pancreatic cancer; BC, breast cancer; LC, lung cancer; SCLC, small cell lung cancer; SC, stomach cancer; BCa, bladder cancer; EC, esophageal carcinoma; HNSCC, head and neck squamous cell carcinoma; UC, urothelial carcinoma; PC, prostate cancer; CC, cervical cancer; ECa, endometrial cancer; AST, advanced solid tumor; CRC, colorectal cancer; DTC, differential thyroid cancer; MM, multiple myeloma; PDAC, pancreatic ductal adenocarcinoma; PTC, papillary thyroid cancer.
Anti Cd19 Car T Cells (With Hla E Transgene) Pbcar 19b, supplied by Baxalta Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Summary of drugs targeting cell cycle-related proteins and undergoing clinical research. Abbreviations: OS, osteosarcoma; LMS, leiomyosarcoma; SS, synovial sarcoma; OC, ovarian cancer; NSCLC, non-small cell lung cancer; PANC, pancreatic cancer; BC, breast cancer; LC, lung cancer; SCLC, small cell lung cancer; SC, stomach cancer; BCa, bladder cancer; EC, esophageal carcinoma; HNSCC, head and neck squamous cell carcinoma; UC, urothelial carcinoma; PC, prostate cancer; CC, cervical cancer; ECa, endometrial cancer; AST, advanced solid tumor; CRC, colorectal cancer; DTC, differential thyroid cancer; MM, multiple myeloma; PDAC, pancreatic ductal adenocarcinoma; PTC, papillary thyroid cancer.

Journal: Heliyon

Article Title: The role of cell cycle-related genes in the tumorigenesis of adrenal and thyroid neuroendocrine tumors

doi: 10.1016/j.heliyon.2024.e41457

Figure Lengend Snippet: Summary of drugs targeting cell cycle-related proteins and undergoing clinical research. Abbreviations: OS, osteosarcoma; LMS, leiomyosarcoma; SS, synovial sarcoma; OC, ovarian cancer; NSCLC, non-small cell lung cancer; PANC, pancreatic cancer; BC, breast cancer; LC, lung cancer; SCLC, small cell lung cancer; SC, stomach cancer; BCa, bladder cancer; EC, esophageal carcinoma; HNSCC, head and neck squamous cell carcinoma; UC, urothelial carcinoma; PC, prostate cancer; CC, cervical cancer; ECa, endometrial cancer; AST, advanced solid tumor; CRC, colorectal cancer; DTC, differential thyroid cancer; MM, multiple myeloma; PDAC, pancreatic ductal adenocarcinoma; PTC, papillary thyroid cancer.

Article Snippet: Allogeneic anti-CD19 CAR T cells (with HLA-E transgene) , PBCAR-19B(Baxalta/Precision BioSciences) , CD19-expressing malignancies , Phase I , [ ] .

Techniques: shRNA, CRISPR, Expressing

Latest advances in allo-CAR-T preclinical studies

Journal: Cancer Cell International

Article Title: Recent updates on allogeneic CAR-T cells in hematological malignancies

doi: 10.1186/s12935-024-03479-y

Figure Lengend Snippet: Latest advances in allo-CAR-T preclinical studies

Article Snippet: HLA-E CAR-T , CD22, CD123 , TRAC and B2M K/O and NK inhibitor overexpression , TALEN ® , Cellectis/USA Institut Paoli-Calmettes/Franc , B-cell malignancies , 2022 , [ ] .

Techniques: Triple Knockout, CRISPR, Expressing, Disruption, Over Expression, Virus